Summary: The DICS database is a dynamic web repository of computationally predicted functional modules from the human protein-protein interaction network. It provides references to the CORUM, DrugBank, KEGG, and Reactome pathway databases. DICS can be accessed for retrieving sets of overlapping modules and protein complexes that are significantly enriched in a gene list, thereby providing valuable information about the functional context. Availability: http://mips.gsf.de/proj/dics Supplementary information: Supplementary information on data sets and methods is available on the web-server. Contact: sabine.dietmann@googlemail.com