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Regina Bohnert, Ph.D.
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Polymorphism Detection in Rice
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Kenneth L McNally, Kevin L Childs, Regina Bohnert, Rebecca M Davidson, Keyan Zhao, Victor J Ulat, Georg Zeller, Richard M Clark, Douglas R Hoen, Thomas E Bureau, Renee Stokowski, Dennis G Ballinger, Kelly A Frazer, David R Cox, Badri Padhukasahasram, Carlos D Bustamante, Detlef Weigel, David J Mackill, Richard M Bruskiewich, Gunnar Rätsch, C. R Buell, Hei Leung, and Jan E Leach (2009)
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice
Proceedings of the National Academy of Sciences, 106(30):12273-8.
Rice, the primary source of dietary calories for half of humanity, is the first crop plant for which a high-quality reference genome sequence from a single variety was produced. We used resequencing microarrays to interrogate 100 Mb of the unique fraction of the reference genome for 20 diverse varieties and landraces that capture the impressive genotypic and phenotypic diversity of domesticated rice. Here, we report the distribution of 160,000 nonredundant SNPs. Introgression patterns of shared SNPs revealed the breeding history and relationships among the 20 varieties; some introgressed regions are associated with agronomic traits that mark major milestones in rice improvement. This comprehensive SNP data provides a foundation for deep exploration of rice diversity and gene–trait relationships and their use for future rice improvement.
Epub July 13, 2009.
Link to PubMed entry
