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Polymorphic Region Detection in A. thaliana

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Georg Zeller, Ph.D.

Georg Zeller, Ph.D.

Detecting polymorphic regions in the A. thaliana genome using Hidden Markov Support Vector Machines has been my main focus within the array-based resequencing project. Polymorphic regions typically correspond to clusters of small polymorphisms (SNPs and indels), but also contain large deletions. As these types of polymorphisms are impossible or very difficult to identify with SNP calling methods, polymorphic region predictions ideally complement SNP calls.
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