Research Interests:

Spliced Alignments for ESTs, cDNAs, and Next-Generation Sequencing Reads:

The task of mapping RNA-Seq reads back to a genome is far from trivial. Many different algorithms were developed over the past decade. Especially the subgroup of spliced aligners is of great interest for RNA-Seq analysis. I am interested in the performance of the different methods and their alignment behaviour. I further analyse what effect filtering of alignments and the selection of true alignments has to different downstream analyses. More information about this topic is available here